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- INDEX
-
- 1 - General
- 2 - Brief description
- 3 - Installation
- 4 - Using GNUPLOT with GEPASI
-
- ======================================================================
- 1 - General
-
- This is GEPASI 2.0, a general purpose simulator of metabolic pathways.
- It is a directed towards research and education; it is meant to be a
- very useful tool for modelling biochemical pathways, chemical
- reactions,etc. GEPASI is free software covered by the GNU general
- public license, version 1.
-
- This version of GEPASI runs under MS-Windows 3.0 and 3.1 in 386
- enhanced mode, on 80386SX and above microprocessors. A maths
- co-processor is not needed but should accelerate the simulations by at
- least a factor of 10.
-
- ======================================================================
- 2 - Brief description
-
- In order to simulate bichemical pathways, the user must first define
- the reactions that are part of the pathway, all its parameters and
- initial concentrations of the metabolites (chemical species). GEPASI
- then determines the dynamics and steady state (if there is one),
- including the coefficients defined in Metabolic Control Analysis.
- GEPASI can be used to study metabolic regulation, chemical and enzyme
- kinetics including oscillatory (limit cycle) and chaotic reactions.
-
- The file GEPASI.WRI contains a cut-down version of a paper to appear
- in "Modern trends in Biothermokinetics", edited by J.-P. Mazat, S.
- Schuster and M. Rigoulet and published by Plenum Press with a short
- description of GEPASI. Another more detailed paper will shortly appear
- in the journal "Computer Applications in the Biosciences".
-
- For more detailed information see the help file (GEPASI.HLP). The
- subjects of metabolic simulation and metabolic control analysis are
- discussed in the mailing list btk-mca. To subscribe to this list send
- a mail message to biosci@net.bio.net, post to the list to
- btk-mca@net.bio.net. Alternatively this list can be accessed via the
- usenet newsgroup bionet.metabolic-reg
-
- ======================================================================
- 3 - Installation
-
- a) from a disk
-
- 1 - put the installation disk in one drive (for example A:)
- 2 - In MS-Windows' Program Manager select File-Run and enter
- A:SETUP.EXE
-
- b) from the zip file
-
- 1 - unzip all files to a disk or directory
- 2 - In MS-Windows' Program Manager select File-Run and enter
- A:SETUP.EXE (or the complete path where you've unzipped
- the files to)
-
- ======================================================================
- 4 - Using GNUPLOT with GEPASI
-
- To facilitate and speed up the production of plots of the data
- generated by GEPASI, this can link to the popular freeware program
- GNUPLOT. GNUPLOT has been included in GEPASI's distribution disks.
- If you obtained GEPASI from an on-line archive or a CD-ROM then you
- need to get GNUPLOT as well; look in directories named 'windows3' or
- 'plot'.
-
- Instructions to make GEPASI aware of your copy of GNUPLOT (not needed
- for the diskette version):
-
- after installing GNUPLOT,
-
- 1 - In GEPASI - Simulation, select Plot...
- 2 - after pressing OK, find the file WGNUPLOT.EXE in the directory
- where you've installed GNUPLOT, select it and press ENTER.
- 3 - from now on use Plot... to make your plots!
-
- GEPASI 2.0 (c) 1989,1992,1993 by Pedro Mendes.
- prm@aber.ac.uk
-